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ABC转运蛋白介导离子跨膜运输的研究进展
郜红建,广敏,徐佳佳,史书林
0
(安徽农业大学资源与环境学院农田生态保育与污染防控安徽省重点实验室,合肥 230036; 安徽农业大学茶与食品科技学院茶树生物学与资源利用省部共建国家重点实验室,合肥 230036)
摘要:
腺苷三磷酸结合盒转运蛋白(ATP-binding cassette transporter,ABC转运蛋白)是一类大量存在于原核生物及真核生物的跨膜转运蛋白,其种类繁多、家族庞大且功能多样,主要功能是利用ATP水解产生的能量将底物进行逆浓度梯度跨膜运输,同时还参与抗原传递、信号传导和细胞解毒等很多重要的生物生理过程。综述了ABC转运蛋白的结构特点、跨膜吸收机制及影响因素,为研究ABC转运蛋白跨膜吸收转运养分离子及其抵抗非生物逆境胁迫提供理论支撑和研究思路。
关键词:  ABC转运蛋白  跨膜运输  离子吸收  机制
DOI:10.13610/j.cnki.1672-352x.20190717.015
基金项目:安徽省自然科学基金青年项目(1808085QC56)资助。
Research progress of ABC transporter mediated ion transmembrane transportation
GAO Hongjian,GUANG Min,XU Jiajia,SHI Shulin
(Anhui Province Key Laboratory of Farmland Ecological Conservation and Pollution Prevention, School of Resources and Environment of Anhui Agricultural University, Hefei 230036; State Key Laboratory of Tea Plant Biology and Utilization, School of Tea and Food Science and Technology of Anhui Agricultural University, Hefei 230036)
Abstract:
ATP-binding cassette transporter is a type of transmembrane transporter family and is ubiquitously found in prokaryotes and eukaryotes. It has a wide variety, a large family and diverse functions, whose main function is to transport the substrate through the reverse concentration gradient across the membrane by using the energy generated by ATP hydrolysis. It also participates in many important physiological processes such as antigen transfer, signal transduction and cell detoxification and etc. In this paper, the structural characteristics, transmembrane transportation mechanism and influencing factors of ABC transporters were reviewed. It provides a theoretical basis and research ideas for studying the ABC transporters mediated ions transmembrane transportation and resistance to abiotic stress in plants.
Key words:  ABC transporters  transmembrane transportation  ions absorption  mechanisms

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