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萹蓄的化学成分及药理作用研究进展
徐燕,李曼曼,刘增辉,王海燕,蒋家月
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(安徽农业大学教育部和农业部茶叶生物化学与生物技术重点实验室,合肥 230036;安徽省医学科学研究院,合肥 230061)
摘要:
萹蓄为常用中药, 具有清热利尿、解毒驱虫、消炎、止泻等功效。现代药理研究也证明其具有利尿、降压、抑菌、抗氧化和保肝等作用。迄今为止,萹蓄中已分离鉴定的化合物主要是黄酮类、酚酸类化合物,其次是苯丙素类、生物碱类、醌类、糖类化合物等,此外,萹蓄中还含有丰富的氨基酸和人体必需的常量和微量元素等。查阅了近40年的萹蓄文献资料, 对其化学成分和药理作用进行系统、全面的综述, 为其进一步开发利用提供参考。
关键词:  萹蓄  黄酮类化合物  酚酸类化合物  药理作用
DOI:
基金项目:安徽农业大学人才启动基金资助。
Research progress in chemical constituents and pharmacological activities of Polygonum aviculare L.
XU Yan,LI Man-man,LIU Zeng-hui,WANG Hai-yan,JIANG Jia-yue
(Key Laboratory of Tea Biochemistry and Biotechnology, Ministry of Education and Agriculture, Anhui Agricultural University, Hefei 230036;Anhui Academy of Medical Sciences, Hefei 230061)
Abstract:
Polygonum aviculare L. is a traditional Chinese medicine and commonly used in folkloric medicine. Modern pharmacological studies have proven that it has diuresis, hypotensive and antimicrobial activities, anti-lipid peroxidation and liver protective effects and so on. Many compounds have been isolated from P. aviculare L., and they are flavonoids, phenolic acids, phenylpropanoids, alkaloids, quinones, saccharides. P. arviculare L. also has essential elements of the human body and amino acids. This paper reviews research progress in the chemical constituents and pharmacological activities of P. aviculare L. to provide references for further development and its utilization.
Key words:  Polygonum avculare L.  flavonoids  phenolic acids  pharmacological activities

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