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山羊内毒素性DIC病症中血红细胞和氧自由基代谢的变化
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摘要:
用内毒素诱导建立山羊DIC模型,检测血红细胞,SOD和MDA的变化,结果表明,模型组血红细胞聚集指数和血浆粘度下降,SOD活力显著下降,MDA含量显著上升,提示DIC时存在血红细胞变形和氧自由基损伤。
关键词:  弥漫性 血管内凝血 羊病 山羊 内毒素性
DOI:
基金项目:
Changes in Red Cells and Metabolism of Oxygen Free-radicals in Enterotoxigenic DIC Goats
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Abstract:
DIC model of goat was developed using enterotoxigen induction and changes of red cells,SOD and MDA was also investigeted.It was found that the aggregation index of red cells,viscosity of plasma and SOD activity of treated goats decreased significantly while MDA content increased significantly,suggesting misshape of red cells and damage of oxygen free radicals in DIC goats.
Key words:  Disseminated intravascular coagulation (DIC) Super oxide dismutase (SOD) Malondialdehyde (MDA) Oxygen free-radical

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