In order to clarify the effects of different fertilization model under nitrogen-reducing condition on the growth and fertilizer utilization efficiency of rice stubble flue-cured tobacco, a single factor experiment with randomized block was used to study the effects of different fertilization modes on root growth, above-ground growth, dry matter and nutrient accumulation and distribution, and fertilizer utilization efficiency of flue-cured tobacco. The results showed that the root promotion and nitrogen reduction fertilization model which was 22.22% nitrogen reduced from traditional fertilization (162.0 kg·hm^-2) was beneficial to promote the root growth and above-ground growth of flue-cured tobacco, and could increase the dry matter accumulation of tobacco plants and that of tobacco leaves during tobacco growth period, and increase the total nitrogen accumulation of tobacco plants and the accumulation of nitrogen and potassium of tobacco leaves. The root promotion and nitrogen reduction fertilization model could improve the nitrogen absorption efficiency by 21.98%, the nitrogen utilization efficiency by 10.39 kg·kg^-1 and the nitrogen accumulation efficiency by 34.95%.The root promotion and nitrogen reduction fertilization model could promote the tobacco plant growth, improve the nutrient absorption capacity and the fertilizer utilization efficiency of flue-cured tobacco. The result provides a theoretical reference for the