Seedlings of Lycopersicon esculentum were applied with four proportions of camellia cake organic fertilizer. The height, diameter, dry weight, chlorophyll content, soluble sugar content, root activity, fruiting rate, and soluble solids content were determined during the growing period. The effects of camellia cake organic fertilizer on the growth index, physiological indicators, fruiting rate, and seedling quality were analyzed according to the data. The results showed that camellia cake organic fertilizer increased seedling height and diameter, dry weight, chlorophyll content, soluble sugar content, root activity, and fruiting rate and improved the fruit quality. The proportion of 30% camellia cake organic fertilizer and 70% basal soil gave the best result. It was suggested that camellia cake is a suitable organic fertilizer for growing Lycopersicon esculentum seedlings.