Using Yannong19 and Lankaoaizao8 as material, we studied the effects of 3 densities and 3 ratios of base and top-dressing nitrogen fertilizer on the yield and their constituent elements of multi-panicle wheat variety and large-panicle wheat variety. The results indicated that: Increase of sowing density could help to increase effective panicles per unit area of different panicle-type wheat, but decrease the grain number per panicle and 1000-grain weight. And increasing of ratio of base and top-dressing nitrogen fertilizer showed positive effects on 1000-grain weight of different panicle-type wheat, and had negative effects on grain number per panicle, but had indistinctive effects on effective panicles per unit area. We used the intermediate density (300×10⁴hm^-2) and 5:5 ratio of base and top-dressing as the treatment for Yannong19, and its output was closed to super-high-yield level. When the treatment reached high-density (412.5×10⁴ hm^-2) and 7:3 ratio of base and top-dressing nitrogen fertilizer for Lankaoaizao8, its yield reached the highest level. Based on the combination of density and ratio of base and top-dressing nitrogen fertilizer and yield, two binary regression models were put forward. Combination of 5:5 ratio of base and top-dressing nitrogen fertilizer and 328.4×10⁴ basic seedling per hectare were the best for Yannong19, and its optimizing production could reach to 8 725.3kg hm^-2. With regard to Lankaoaizao8, Combination of 7:3 ratio of base and top-dressing nitrogen fertilizer and 421.2×10⁴ basic seedling per hectare were optimal, and its optimizing production could reach to 7 441.1kg hm^-2.